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To this end, we used small molecules that reduce PrP expression by different mechanisms

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As therapy, BPC 157, (10 µg/kg, 10 ng/kg, per-orally, in drinking water until sacrifice, or alternatively, intraperitoneally, first application at 30 min after surgery, last at 24 h before sacrifice), evidently rescues rats with the duodenocolic fistulas, since very beginning